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Yes, by all means it can be used. It is recommended to take the supplement (a Synbiotic capsule and a Postbiotic capsule) during an antibiotic therapy and to continue the supplementation for the period of 7-10 days after the end of the antibiotic therapy. Preferably, ProBactilardii® should be taken an hour after an antibiotic or between antibiotic doses.

CAN DUOLIFE'S CLINICAL FORMULA PROBACTILARDII® BE USED DURING AN ANTIBIOTIC THERAPY AND HOW LONG SHOULD THE SUPPLEMENTATION LAST? 

The combination of those two specific bacteria strains improves the protection of the digestive system against pathogenic bacteria, viruses or fungi which cause diarrhoea and infections, regulates intestinal peristalsis, helps relieve constipation, and - what is important and proven in clinical tests - supports psychological functions in healthy humans, helping them stay in an optimal mood, and protects against detrimental impact of stress on the functions of the alimentary tract and the central nervous system. These strains may lead to less intensive gastrointestinal issues caused by excessive emotions and stress.

HOW DOES THE COMBINATION OF Bifidobacterium longum Rosell® R0175 and Lactobacillus helveticus Rosell® R0052 SUPPORT OUR ORGANISM?

Clinical tests confirm that the combination of Bifidobacterium longum Rosell® R0175 and Lactobacillus helveticus Rosell® R0052 has a positive impact on the gut-brain axis, contributing to an improved functioning of the digestive system and the central nervous system. The number and proportions of the bacteria strains in DuoLife's food supplement - ProBactilardii are equivalent to those used in clinical tests.

WHICH STRAINS OF DUOLIFE'S FOOD SUPPLEMENT - PROBACTILARDII® HAVE A POSITIVE IMPACT ON THE GUT-BRAIN AXIS? 

The gut-brain axis explains the links between the digestive system and the central nervous system (CNS) in humans. It is bidirectional communication, where the brain communicates with the guts and the guts may affect the brain. The communication may be direct via nerve fibres or indirect by means of hormones, neurotransmitters, cytokines and metabolites which are produced with the involvement of intestinal bacteria.

WHAT IS THE GUT-BRAIN AXIS AND WHAT IS ITS FUNCTION?

DuoLife's food supplement - ProBactilardii® supports restoration of intestinal microflora, for example, in the case of:

  • people who every day want to enhance the optimal functioning of their alimentary tract
  • people with gastrointestinal issues related to disorders of the natural intestinal microflora, including constipation or diarrhoea
  • people with digestive problems related to excessive stress
  • people during and after antibiotic treatment (antibacterial and/or antifungal)
  • people planning trips, especially to exotic and tropical countries, with a different menu, to be used before and during the trip
  • people who want to support the functions of their immune system, including those with reduced immunity due to excessive stress
  • people who want to support optimal functions of their central nervous system, including optimal mood
  • people with mood swings
  • people with lactose intolerance
  • the elderly, weak, undernourished

WHAT IS THE INTENDED PURPOSE OF PROBACTILARDII® FOOD SUPPLEMENT AND WHO CAN USE IT?

Acacia fibre belongs to probiotics; it stimulates the growth of natural microflora, favours optimal functions of the alimentary tract, improves peristalsis and regulates bowel movements.

WHAT IS ACACIA FIBRE RESPONSIBLE FOR? 

The butyric acid contained in ProBactilardii® food supplement belongs to postbiotics. It favours the optimal condition of intestines, improves their peristalsis and barrier functions, and provides nutrients to epithelial cells in the intestines.

WHAT IS THE ROLE OF THE BUTYRIC ACID CONTAINED IN DUOLIFE'S CLINICAL FORMULA PROBACTILARDII®? 

The packaging contains two pillboxes - a Synbiotic and a Postbiotic.  One pillbox has Synbiotic capsules which contain a prebiotic (in form of acacia fibre) and proprietary BACTILARDII® probiotic formula. Another pillbox has Postbiotic capsules with a formula based on butyric acid.

THE PACKAGING CONTAINS TWO PILLBOXES. WHAT IS THE DIFFERENCE BETWEEN THEM? 

Intestinal microflora means micro-organisms - predominantly bacteria, but also fungi and viruses - which live in the human alimentary tract and affect the functioning of the whole organism; they are also an important element in the prophylaxis of many diseases. Intestinal microflora of a healthy human is made up of almost 100 trillion beneficial microbes. 

WHAT IS INTESTINAL MICROFLORA?

The bacteria strains for ProBactilardii® food supplement are supplied by a global expert in probiotics - the Canadian company Lallemand. BACTILARDII® formula has been developed for the exclusive use of DuoLife company.

WHO SUPPLIES THE BACTERIA STRAINS FOR THE PRODUCTION OF PROBACTILARDII® FOOD SUPPLEMENT? 

The number of bacteria at the moment of probiotic production is always high; however, over time it decreases substantially, for example, due to improper protection of the strains, which - in turn - leads to their death. Therefore, only those probiotic products whose producers reveal the information about and guarantee the number of bacteria at the end of the product's shelf life provide reliable and trustworthy information about the actual number of microbes with invaluable probiotic effects contained in the given product. ALWAYS check if the producer declares the number of live micro-organisms at the end of the product's shelf life or only at the time of production. These numbers are not equivalent!

WHY SHOULD WE MAKE SURE THAT THE DECLARED NUMBER OF BACTERIA IS THE SAME AS THE NUMBER OF BACTERIA AT THE END OF THE PRODUCT'S SHELF LIFE? 

It is very important to provide our organism with live bacteria and yeast strains, as only such strains may be subject to adhesion, i.e. clinging, to intestinal mucus. Adhesion to the intestinal wall is a prerequisite for the probiotic effects of bacteria and yeasts. 

WHY IS IT IMPORTANT THAT A PROBIOTIC CONTAIN LIVE BACTERIA AND YEAST STRAINS?

In total, there are 9 billion LIVE, freeze-dried and selected bacteria and yeast cultures GUARANTEED in the product AT THE END OF ITS SHELF LIFE. 

HOW MANY BACTERIA DOES DUOLIFE'S FOOD SUPPLEMENT - CLINICAL FORMULA PROBACTILARDII® CONTAIN?

These annotations denote a specific, selected and branded bacteria or yeast strain used in a probiotic. The effectiveness of a probiotic is closely linked to the high quality of its strains. Thanks to these annotations it is possible to check how well the particular strain has been tested and to find the relevant clinical tests. In DuoLife's food supplement - Clinical Formula ProBactilardii® all bacteria and yeast strains are selected and branded, and have clinically confirmed effectiveness.

WHAT DO THE ANNOTATIONS OF ROSELL® R0071, ROSELL® R0175, FOR EXAMPLE, MEAN WHEN ADDED TO THE NAME OF A BACTERIA STRAIN OR WHAT DOES THE NUMBER CNCM I-1079 STAND FOR WHEN ADDED TO THE NAME OF A YEAST STRAIN?

DuoLife's Clinical Formula ProBactilardii® is a food supplement consisting of 2 complementary capsules. One capsule (Synbiotic) contains a prebiotic in form of acacia fibre and a probiotic - freeze-dried, live bacteria cultures of Bifidobacterium bifidum Rosell® R0071, Bifidobacterium longum Rosell® R0175, Lactobacillus helveticus Rosell® R0052 and Lactobacillus rhamnosus Rosell® R0011 as well as the yeast strain of Saccharomyces boulardii CNCM I-1079, which together make the proprietary DuoLife probiotic mixture of BACTILARDII® 

Another capsule (Postbiotic) contains a postbiotic - butyric acid - in form of glycerol tributyrate (tributyrine).

WHAT IS THE COMPOSITION OF DUOLIFE'S FOOD SUPPLEMENT - CLINICAL FORMULA PROBACTILARDII®?

Intestinal dysbiosis is microbiological imbalance consisting in changes in the amount and functioning of intestinal microflora. Malfunctioning microflora may lead to development of many ailments related to, but not limited to, the functioning of the digestive system, immune system or central nervous system.  Supplementation with probiotics restores the balance of intestinal microflora.

WHAT IS INTESTINAL DYSBIOSIS?

Postbiotics are products of metabolism produced and secreted by the beneficial intestinal microflora which feeds on fibre.

WHAT IS A POSTBIOTIC?

A synbiotic is a mixture of probiotics and prebiotics. When we use a synbiotic we supplement our natural microflora with beneficial microbes and, at the same time, provide them with a nutrient medium in form of a prebiotic, e.g. acasia fibre. Synbiotics are recognised as exceptionally effective, e.g. in maintaning the good condition of intestinal microflora.

WHAT IS A SYNBIOTIC?

Yes, they have. The effectiveness of the individual bacteria strains contained in DuoLife's Clinical Formula ProBactilardii® was confirmed in numerous clinical tests (over 100 clinical tests). Please familiarise yourself with the bibliography of the educational chart which can be downloaded from the tab: Product Description in MDL store.

HAVE THE PROBIOTIC STRAINS IN PROBACTILARDII® FOOD SUPPLEMENT BEEN CLINICALLY TESTED?

Yes, ProBactilardii® Food Supplement can be used by vegans and vegetarians.

CAN DUOLIFE'S FOOD SUPPLEMENT - CLINICAL FORMULA PROBACTILARDII® BE USED BY VEGANS AND VEGETARIANS? 

Yes. The raw materials used in the product are not obtained from genetically modified organisms. The product does not contain any additional artificial fillers. The product can be used by people with gluten intolerance.  

IS DUOLIFE'S CLINICAL FORMULA PROBACTILARDII® FREE FROM ARTIFICIAL FILLERS, GMO AND GLUTEN?

Both the synbiotic and the postbiotic are contained in natural HPMC capsules with a delayed time of release which guarantee additional protection of their contents against the adverse effects of external conditions and stomach acid. BIO-SUPPORT™ technology protects against the adverse effects of external conditions, stomach acid and bile salts.

The patented immediate Activ-Vial™ packaging minimises the access of moisture from the air and light to the capsules in the container.

HOW ARE THE BACTERIA STRAINS IN PROBACTILARDII® FOOD SUPPLEMENT PROTECTED?

Proprietary BIO-SUPPORT™ technology protects the bacteria and yeast strains in the product against the adverse effects of external conditions during the production and storage, and against the adverse effect of the stomach acid and bile salts in the alimentary tract, thus enabling the probiotic strains to reach the large intestine without losing their biological activity.

WHAT IS THE PURPOSE OF BIO-SUPPORT™ TECHNOLOGY?

Patented, innovative, drug-certified ACTIV-VIAL™ packaging from the American company CSP Technologies - a white opaque container with a pharmaceutical standard for probiotics made of the highest quality material with Activ-Polymer™ lining, guaranteeing no access of moisture from the air and light to the capsules contained in the package, at a level better than the classic blister pack. Additionally, the packaging is equipped with a system protecting against the first opening, which guarantees that the product is brand new and has not been previously tampered with by third parties.

WHAT MAKES THE PATENTED ACTIV-VIAL™ PACKAGING WITH ACTIV-POLYMER™ LINING DIFFERENT? 

ProBactilardii® Food Supplement should be used within 30 days as of the opening of the packaging.

WHAT IS THE USE-BY DATE OF PROBACTILARDII® FOOD SUPPLEMENT AS OF THE OPENING OF THE PACKAGING? 

There is no need to do so, as long as it is stored away from the sources of heat (radiator) and kept at room temperature (20-25⁰ C).

UPON OPENING, SHOULD THE PILLBOX BE KEPT IN A FRIDGE? 

No. The product does not require storage in a fridge. The stability and viability of microbes in BACTILARDII® formula over the storage period of 24 months at a temperature of 20-25 ⁰C have been tested and laboratory confirmed. Therefore, the optimal viability and the specified number of live microbes are guaranteed when the product is stored at room temperature until the end of its expiry date.  Additionally, the patented Activ-Vial™ packaging with Activ-Polymer™ lining protects the capsules in the container against moisture from the air and against light.

DOES PROBACTILARDII® FOOD SUPPLEMENT REQUIRE STORAGE IN A FRIDGE?

Yes. In the case of trips to tropical countries or to countries with a low level of hygiene standards (developing countries), it is recommended to use ProBactilardii® 5 days before the trip, during the entire trip and for 5 days after the trip.

CAN DUOLIFE'S CLINICAL FORMULA PROBACTILARDII® BE TAKEN BEFORE A TRIP?

ProBactilardii® should not be used in the case of oversensitivity to any of the product's ingredients. The Postbiotic capsules should not be given to children under 7 years of age; the Synbiotic capsules should not be given to children under 3 years of age and should not be used by people suffering from severe pancreas inflammation and disorders of the immune system. The use of the capsules should be consulted with a doctor in the case of patients who undergo an immunosuppressive therapy, oncological treatment, chemotherapy and radiotherapy.

WHEN SHOULD DUOLIFE'S CLINICAL FORMULA PROBACTILARDII® NOT BE USED? 

The Synbiotic capsules can be used upon prior consultation with a doctor. 

The Postbiotic capsules are not recommended to pregnant women and breast-feeding mothers.

CAN PROBACTILARDII® FOOD SUPPLEMENT BE USED BY PREGNANT WOMEN AND BY BREAST-FEEDING MOTHERS?

Preferably, the capsules should be washed down with water which is cool or at room temperature.

WHAT SHOULD DUOLIFE'S CLINICAL FORMULA PROBACTILARDII® BE WASHED DOWN WITH? 

In case of problems with swallowing a capsule, its content may be poured into a spoon and administered directly to the child's mouth or, additionally, the substance in the spoon may be dissolved in a small amount of water at room temperature and consumed directly afterwards.

WHAT SHOULD BE DONE IF A CHILD HAS PROBLEMS WITH SWALLOWING A CAPSULE?

The Synbiotic capsules can be given to children over 7 years of age. They may be given to children over 3 years of age upon consultation with a physician. The capsules with the synbiotic are not recommended for children under 3 years of age.

The Postbiotic capsules can be given to children over 12 years of age. Children from 7 to 12 years of age: the use is allowed after prior consultation with a doctor. The capsules with the postbiotic are not recommended for children under 7 years of age.

CAN PROBACTILARDII® FOOD SUPPLEMENT BE GIVEN TO CHILDREN? 

As a rule, one capsule of the Synbiotic and one capsule of the Postbiotic per day is enough. In the case of a long antibiotic therapy or a need to provide extra support to the intestines, for instance in the case of severe diarrhoea, it may be necessary to use two capsules (combined) twice a day.

WHO SHOULD USE ONE AND WHO SHOULD USE TWO CAPSULES OF THE SYNBIOTIC AND THE POSTBIOTIC PER DAY?

The capsules may be taken together or separately.

MUST THE CAPSULES ALWAYS BE TAKEN TOGETHER OR CAN THEY BE TAKEN SEPARATELY, FOR EXAMPLE: THE SYNBIOTIC IN THE MORNING AND THE POSTBIOTIC IN THE EVENING?

Adults and children over 12 years of age: 1 capsule from each container per day to be washed down with cool water. The combined use involves 2 capsules taken simultaneously – the synbiotic in the first capsule and the postbiotic in the second capsule. If necessary, the use of each capsule may be increased to twice a day.

HOW TO USE DUOLIFE'S FOOD SUPPLEMENT - PROBACTILARDII® (ADULTS)?

In the case of a temporary (ad hoc) use of antibiotics, for example, the supplementation should last for the entire period of the antibiotic therapy and should be continued for the period of 7-10 days after its completion; in the case of trips to tropical countries, ProBactilardii® food supplement should be used 5 days before the trip, during the whole trip and for 5 days after the trip.

If used to support the immune system, alimentary tract or nervous system, the recommended period of use is minimum a month, preferably 3 months. 

HOW LONG SHOULD SUPPLEMENTATION WITH DUOLIFE'S CLINICAL FORMULA PROBACTILARDII® LAST? 

ProBactilardii® Food Supplement has an extensive safety profile. ProBactilardii® Food Supplement should be used at least 2 hours after the use of anti-diarrhoae adsorbents (e.g. Smecta, activated carbon), because they can cause inactivation of beneficial bacteria and yeasts.

ARE THERE ANY INTERACTIONS BETWEEN DUOLIFE'S FOOD SUPPLEMENT - CLINICAL FORMULA PROBACTILARDII® AND OTHER FOOD SUPPLEMENTS OR MEDICATIONS? 

DuoLife Clinical Formula ProBactilardii®

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